Molecular & Cellular Biology Faculty Research Areas
Learn about faculty research in the following departments and institutes that comprise the Molecular and Cellular Biology graduate program.
Biological Sciences Department
in the College of Arts and Sciences
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Ronan CarrollResearch Interests-- Molecular mechanisms employed by bacteria that allow them to cause disease in humans with a focus in regulation of bacterial virulence gene expression
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Donald Holzschu
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Shawn KuchtaResearch Interests-- Integrate population genetics, phylogeography, and phylogenetics to study the evolution of biodiversity, including species formation, biogeography, natural selection, and taxonomy.
-- Current studies focus with salamanders, turtles, and damselflies. -
Daewoo LeeResearch Interests-- Functional dissection of molecular elements mediating central synaptic transmission in Drosophila
-- Molecular and cellular bases of neuromodulation and synaptic plasticity. Mechanisms of selective dopaminergic cell loss in Parkinson's disease -
Corinne NielsenResearch Interests-- Genetic regulation of mammalian neurovascular development, physiology and pathophysiology
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Tomohiko SugiyamaResearch Interests-- Biochemical study of DNA recombination: Meiotic recombination and DNA double-strand-break repair.
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Nathan WeyandResearch Interests-- Bacterial pathogenesis, complement evasion, asymptomatic carriage, horizontal gene transfer of antimicrobial resistance, biofilm formation.
Chemistry & Biochemistry Department
in the College of Arts and Sciences
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Stephen BergmeierResearch Interests-- We broadly define medicinal chemistry as the study of drug design, drug synthesis, and drug action.
-- Our research seeks to advance the areas of drug design as well as drug synthesis. -
Michael HeldResearch Interests-- The biochemistry of plant cell wall biosynthesis
-- Vesicle trafficking of nascent plant cell wall cargo
-- Plant cell walls as sources of lignocellulosic bioenergy feedstocks -
Jennifer HinesResearch Interests-- Structural biology and medicinal chemistry of nucleic acids
-- RNA as a therapeutic target for the treatment of cancer as well as viral and bacterial infections. -
Justin HolubResearch Interests-- Research in the Holub Laboratory focuses on the development of chemical tools to investigate biological processes.
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Edward Saliba-- Nuclear magnetic resonance (NMR) instrumentation and method development.
-- Bioanalytical/physical/inorganic NMR
-- NMR theory development -
Shiyong WuResearch Interests-- Regulation of eukaryotic protein synthesis initiation and endoplasmic reticulum (ER)-stress. Molecular mediators of UV-induced apoptosis. Natural biological therapeutics for infectious diseases and cancer therapy.
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Mengliang ZhangResearch InterestsForensic Chemistry | Food and Agricultural Chemistry | Metabolomics | Environmental Chemistry |
Material Science
Environmental & Plant Biology Department
in the College of Arts and Sciences
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Burcu AlptekinResearch Interests-- Plant Molecular Biology
-- Plant Genetics
-- Plant Physiology -
Harvey BallardResearch Interests-- Molecular phylogenetic relationships of populations, species and genera, especially in the Violet family; molecular data in conservation genetics, adaptive radiation and speciation processes
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Ahmed FaikResearch Interests-- Study of plant cell wall polysaccharides biosynthesis and metabolism using functional genomics approaches (Bioinformatics, Genomics, Biochemistry, Molecular Biology)
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Zhihua HuaResearch Interests-- Multidisciplinary molecular approaches, included but not limited to molecular and cellular biology, biochemistry, omics, and evolutionary biology to tackle the roles of protein ubiquitylation in plant growth and development
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John SchenkResearch Interests-- Plant Evolution
-- Plant Morphology
-- Phylogenetics -
Morgan VisResearch Interests-- Molecular systematics and population biology of freshwater algae
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Sarah WyattResearch Interests-- Plant growth and development with an emphasis on the use of molecular and genetic tools to study plant responses to environmental stimuli
Biomedical Engineering, Electrical Engineering and Computer Science Departments
in the Russ College of Engineering & Technology
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Lonnie WelchResearch Interests-- Bioinformatics, Computational regulatory genomics, Machine learning, High performance computing
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Douglas GoetzResearch Interests-- Research in biomedical engineering, with expertise in cell to cell adhesion with an emphasis on adhesion events that occur in the circulation
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Tingyue GuResearch Interests-- Preparative and large-scale purification of recombinant proteins; dynamics of liquid chromatography
-- Fermentation
Heritage College of Osteopathic Medicine
Including Biomedical Sciences Department, Diabetes Institute and Ohio Musculoskeletal and Neurological Institute
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Cory BaumannResearch Interests-- Sites and mechanisms that increase the stress buffering capacity of the neuromuscular system, which ultimately can be targeted to improve function and health span in aging, frail and myopathic populations.
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Fabian BenenciaResearch Interests-- Immunity responses in different diseases such as cancer, atherosclerosis or infections. Investigating the factors governing the plasticity of these cells may unhide new targets for immune therapies.
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Karen CoschiganoResearch Interests-- Identification of genes involved in the development of diabetes and its complication, especially in the kidney, using molecular tools and mouse models that mimic human disease.
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Peter CoschiganoResearch Interests-- Genetics and molecular biology of microorganisms that degrade toxic compounds, regulation of gene expression, elucidation of metabolic pathways.
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Tim EtheridgeResearch Areas-- Focusing on muscle disease and optimizing adaptation to nutrition and exercise
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Mario J. GrijalvaResearch Areas-- Molecular diagnosis, immunology and epidemiology of Tropical diseases
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Sharon InmanResearch Areas-- Research involves understanding the mechanisms underlying the protective role of HMG-CoA reductase inhibitors in renal transplantation and ischemia/reperfusion injury
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John KopchickResearch Areas-- We are interested in the molecular and cellular events involved in growth, obesity, and diabetes. We use transgenic and gene disrupted mice as well as genomic and proteomic approaches to study these areas. Overall we would like to determine the mechanisms that result in mammalian growth. Additionally, we would like to determine the genetic defects that result in abnormal growth phenotypes or improper meabolic function.
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Kevin LeeResearch Areas-- Examining the molecular biology of these adipocyte subpopulations and determining their effects on systemic metabolism and physiology.
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Yang Li
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Chunmin LoResearch Areas-- My research interest focuses on control of energy intake and expenditure, gluscose homeostasis, and lipid transport / metabolism.
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Ramiro MalgorResearch Areas-- Understanding how inflammation is involved in the pathogenesis of chronic disease. Our goal is to elucidate the role of inflammation in the pathogenesis of atherosclerosis, diabetes and cancer.
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Kelly McCallResearch Areas-- Research topis: Diabetes, inflammation, autoimmune disease, tumor biology, innate immunity, small molecule therapeutics. Toll-Like receptors and their involvement in the pathogenesis and progression in cancers: thyroid, pancreatic, prostate, breast, colon and malignant melanoma.
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Erin MurphyResearch Areas-- My research focuses on understanding the regulatory mechanisms governing the expression of genes encoding bacterial virulence determinants. In particular I am interested in gene expression controlled by non-coding RNA molecules in response to environmental signals.
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Craig NunemakerResearch Areas-- My lab studies the cells in the pancreas that make and release insulin in order to learn how they help to regulate energy needs of the body and to learn how to fix what goes wrong with the beta-cells in type 2 diabetes.
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Vishwajeet PuriResearch Areas-- Identifying the CIDE proteins and their role in pathogenesis and pathophysiology of obesity, type 2 diabetes, and cardiovascular disease. Puri lab uses various humanized mouse models and human clinical studies to identify molecular pathways regulating these diseases, and identifying potential therapeutic targets.
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Thomas RosolResearch AreasThe Rosol laboratory investigates the pathogenesis of animal models of human cancer, mechanisms and treatment of bone metastasis, and endocrine-responsive cancers.
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Shaohua WangResearch Areas-- We focus largely on the bacterial pathogen studies especially Clostridioides difficile (C. difficile). C. difficile is the most common hospital acquired infections, with high rate of antibiotic resistance and recurrence incidences, became a debilitating public health threat, with no successful preventive and treatment options.