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Monica Burdick

Associate Professor
Chemical and Biomolecular Engineering, Biomedical Engineering
Stocker Center 189
Phone: 740.593.0033

Dr. Burdick earned her Ph.D. in Chemical and Biomolecular Engineering from Johns Hopkins in 2003, and her B.S. in Chemical Engineering from the University of Rochester, where she minored in chemistry and economics and earned a certificate in biomedical engineering. Following her Ph.D., she became a post-doctoral research fellow at the Harvard Medical School and Brigham and Women's Hospital in Boston, MA. In her research, Dr. Burdick applies engineering principles such as fluid dynamics to study how cancer cells move through the body, and how metastasis can be countered.

Research Interests: Colon Cancer, Breast Cancer, Metastatis, Cell Adhesion

All Degrees Earned: Ph.D., Chemical and Biomolecular Engineering, Johns Hopkins, 2003 -- BS, Chemical Engineering, University of Rochester, 1998

Research Report (2)

  • Burdick, M., Hanley, W., Konstantopoulos, K., Sackstein, R. (2005). CD44 on LS174T Colon Carcinoma Cells Possesses E-selectin Ligand Activity. 13. Cancer Research; 65: 5812-5817.
  • Burdick, M., Schnaar, R., Collins, B., Bochner, B., Konstantopoulos, K. (2001). Glycolipids Support E-selectin-Specific Strong Cell Tethering under Flow. Biochemical and Biophysical Research Communications ; 284: 42-49.

Conference Proceeding (1)

  • Burdick, M., McCarty, O., Jadhav, S., Konstantopoulos, K. (2001). Cell-Cell Interactions in Inflammation and Cancer Metastasis. 3. IEEE Engineering in Medicine and Biology; 20: 86-91.

Journal Article, Academic Journal (33)

  • Noori, M., Bodle, S., Showalter, C., Streator, E., Drozek, D., Burdick, M., Goetz, D. (2020). Sticking to the Problem: Engineering Molecular Endoscopic Imaging. 13: 113–124.
  • Martin, E., Malgor, R., Resto, V., Goetz, D., Burdick, M. (2019). Dynamic biochemical tissue analysis detects functional selectin ligands on cancer tissues. 1. 9: 8511.
  • Mohammadalipour, A., Showalter, C., Muturi, H., Farnoud, A., Najjar, S., Burdick, M. (2019). Cholesterol depletion decreases adhesion of non-small lung cancer cells to E-selectin.
  • Goldson, T., Turner, K., Huang, Y., Carlson, G., Caggiano, E., Oberhauser, A., Fennewald, S., Burdick, M., Resto, V. (2019). Nucleolin Mediates the Binding of Cancer Cells to L-selectin under Conditions of Lymphodynamic Shear Stress.
  • Noori, M., Streator, E., Carlson, G., Drozek, D., Burdick, M., Goetz, D. (2018). An Adhesion Based Approach for the Detection of Esophageal Cancer. 747-757.
  • Mohammadalipour, A., Burdick, M., Tees, D. (2018). Deformability of breast cancer cells in correlation with surface markers and cell rolling. 4. 32: 1806-1817. .
  • Reynolds, N., Mohammadalipour, A., Hall, C., Asghari Adib, A., Farnoud, A., Burdick, M. (2018). Galectin-1 Influences Breast Cancer Cell Adhesion to E-selectin via Ligand Intermediaries. 1. 11: 37-52.
  • Mohammadalipour, A., Burdick, M., Tees, D. (2017). Viscoelasticity measurements reveal rheological differences between stem-like and non-stem-like breast cancer cells. 3. 10: 235-248.
  • Noori, M., O'Brien, J., Champa, Z., Deosarkar, S., Lanier, O., Qi, C., Burdick, M., Schwartz, F., Bergmeier, S., McCall, K., Goetz, D. (2017). Phenylmethimazole and a Thiazole Derivative of Phenylmethimazole Inhibit IL-6 Expression by Triple Negative Breast Cancer Cells. 803: 130-137.
  • Carlson, G., Martin, E., Shirure, V., Malgor, R., Resto, V., Goetz, D., Burdick, M. (2017). Dynamic biochemical tissue analysis detects functional L-selectin ligands on colon cancer tissues. 3. 12: e0173747.
  • Yuan, Y., Wu, L., Shen, S., Wu, S., Burdick, M. (2016). Effect of alpha 2, 6 Sialylation on Integrin-mediated Adhesion of Breast Cancer Cells to Fibronectin and Collagen IV. 149. 138-145.
  • Alapati, A., Deosarkar, S., Lanier, O., Qi, C., Carlson, G., Burdick, M., Schwartz, F., McCall, K., Bergmeier, S., Goetz, D. (2015). Simple Modifications to Methimazole that Enhance its Inhibitory Effect on Tumor Necrosis Factor-alpha-Induced Vascular Cell Adhesion Molecule-1 Expression by Human Endothelial Cells. 751: 59-66.
  • Alapati, A., Deosarkar, S., Lanier, O., Qi, C., Carlson, G., Burdick, M., Schwartz, F., McCall, K., Bergmeier, S., Goetz, D. (2015). Simple modifications to methimazole that enhance its inhibitory effect on tumor necrosis factor-α-induced vascular cell adhesion molecule-1 expression by human endothelial cells.. 751: 59-66.
  • Shirure, V., Liu, T., Delgadillo, L., Cuckler, C., Tees, D., Benencia, F., Goetz, D., Burdick, M. (2015). CD44 variant isoforms expressed by breast cancer cells are functional E-selectin ligands under flow conditions. 1. 308: C68-78.
  • Burdick, M., Reynolds, N., Martin, E., Hawes, J., Carlson, G., Cuckler, C., Bates, M., Barthel, S., Dimitroff, C. (2014). Isolation and characterization of chimeric human Fc-expressing proteins using protein A membrane adsorbers and a streamlined workflow. 83. Cambridge, MA.
  • Carlson, G., Martin, E., Burdick, M. (2013). Simultaneously capturing real-time images in two emission channels using a dual camera emission splitting system: Applications to cell adhesion. 79. Cambridge, MA: 4: e50604.
  • Barthel, S., Hays, D., Yazawa, E., Opperman, M., Walley, K., Nimrichter, L., Burdick, M., Gillard, B., Siddiqui , J., Foster, B., Moser, M., Pantel, K., Pienta, K., Charles, D. (2013). Molecular determinants of prostate cancer cell bone extravasation: E-selectin ligands, integrins and GTPases. 2. 73: 942-952.
  • Shirure, V., Reynolds, N., Burdick, M. (2012). Mac-2 Binding Protein is a Novel Eselectin Ligand Expressed by Breast Cancer Cells. 9. 7: e44529 (11 pages).
  • Burdick, M., Henson, K., Delgadillo, L., Choi, Y., Goetz, D., Tees, D., Benencia, F. (2012). Expression of E-selectin ligands on circulating tumor cells: Cross-regulation with cancer stem cell regulatory pathways?. 2: 103 (11 pages).
  • Kummitha, C., Shirure, V., Delgadillo, L., Deosarkar, S., Tees, D., Burdick, M., Goetz, D. (2012). HECA-452 is a Non-Function Blocking Antibody for Sialyl Lewis-x Microsphere Adhesion to Endothelial Expressed E-selectin Under Flow Conditions. 1-2. 384: 43-50.
  • Merzaban, J., Burdick, M., Gadhoum, S., Dagia, N., Chu, J., Fuhlbrigge, R., Sackstein, R. (2011). Analysis of Glycoprotein E-selectin Ligands on Human and Mouse Marrow Cells Enriched for Hematopoietic Stem/Progenitor Cells. 7. 118: 1174-83.
  • Shirure, V., Henson, K., Schnaar, R., Nimrichter, L., Burdick, M. (2011). Glycolipids are Major E-selectin Ligands Expressed by Breast Cancer Cells. 3. 406: 423-9.
  • Wang, L., Shirure, V., Burdick, M., Wu, S. (2011). UVB-Irradiation Regulates VLA-4-Mediated Melanoma Cell Adhesion To Endothelial VCAM-1 Under Flow Conditions. 1. 50: 58-65.
  • Nimrichter, L., Burdick, M., Aoki, K., Laroy, W., Fierro, M., Hudson, S., Von Seggern, C., Cotter, R., Bochner, B., Tiemeyer, M., Konstantopoulos, K., Schnaar, R. (2008). E-selectin receptors on human leukocytes. 9. 112: 3744-3752.
  • Resto, V., Burdick, M., Dagia, N., McCammon, S., Fennewald, S., Sackstein, R. (2008). L-selectin-mediated lymphocyte-cancer cell interactions under low fluid shear conditions. 23. 283: 15816-15824.
  • Burdick, M., Alves, C., Thomas, S., Pawar, P., Konstantopoulos, K. (2008). The Dual Role of CD44 as a Functional P-selectin and Fibrin Ligand in Colon Carcinoma Cell Adhesion. 4. 294: C907-C916.
  • Burdick, M., Chu, J., Godar, S., Sackstein, R. (2006). HCELL is the Major E- and L-Selectin Ligand Expressed on LS174T Colon Carcinoma Cells. 281: 13899-13905.
  • Burdick, M., Lim, L., Hudson, S., Konstantopoulos, K., Bochner, B. (2006). Stimulation of Human Endothelium with IL-3 Induces Selective Basophil Accumulation In Vitro. 176: 5346-5353.
  • Hanley, W., Napier, S., Burdick, M., Schnaar, R., Sackstein, R., Konstantopoulos, K. (2006). Variant Isoforms of CD44 are P- and L-selectin Ligands on Colon Carcinoma Cells. 20: 337-339.
  • Burdick, M., Konstantopoulos, K. (2004). Platelet-Induced Enhancement of Colon Carcinoma Cell Adhesion to Vascular Endothelium under Flow. 2. 287: C539-C547.
  • Burdick, M., McCaffery, J., Kim, Y., Bochner, B., Konstantopoulos, K. (2003). Colon Carcinoma Cell Glycolipids, Integrins and Other Glycoproteins Mediate Adhesion to HUVECs under Flow. 4. 284: C977-C987.
  • McCarty, O., Jadhav, S., Burdick, M., Bell, W., Konstantopoulos, K. (2002). Fluid Shear Regulates the Kinetics and Molecular Mechanisms of Activation-Dependent Platelet Binding to Colon Carcinoma Cells. 2. 83: 836-848.
  • Tachimoto, H., Burdick, M., Hudson, S., Konstantopoulos, K., Bochner, B. (2000). Chemokines Promote Rapid Detachment of Eosinophils from VCAM-1 In Vitro. 165: 2748-2754.


  • Burdick, M., Goetz, D., Malgor, R., Shirure, V., Resto, V. Dynamic biochemical tissue analysis. WO/2013/006405 .
  • Burdick, M., Goetz, D., Malgor, R., Shirure, V., Resto, V. Dynamic biochemical tissue analysis. WO/2013/006405 .