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Brian Clark, PhD

Clark, Brian 11-21
Prof., Physiology & Neuroscience; Osteopathic Heritage Foundation Harold E. Clybourne, D.O., Endowed Research Chair
Irvine 250, Athens Campus


  • Neuromuscular Physiology (PhD), Syracuse University, 2006
  • Exercise Physiology (MS), Syracuse University, 2006
  • Gerontology (Certificate of Advanced Study), Syracuse University, 2006
  • Biology (BS), Western Carolina University, 1998

Summary of Work:

My work centrally seeks to improve the diagnosis, treatment, and prevention of sarcopenia and osteoporosis. The overall goal of my research is to develop effective and implementable interventions that increase neuromuscular and musculoskeletal function and mobility in older adults, and/or patients with orthopedic and neurologic disabilities. I have expertise and experience with basic and applied science human physiology experiments as well as randomized controlled trials. As such, my work is in the area of ‘translational physiology’, as it sits at the intersection of the bench and bedside. Within this scope, my laboratory maintains programmatic efforts in three focused areas: 1) the neuromuscular mechanisms of muscle weakness, fatigue-resistance, and mobility limitations, 2) interventional strategies to enhance physical function and independence in older adults, and 3) enhancing the diagnosis of osteoporosis. My work has been continuously funded by ~ $28 million in extramural support by NIH, NASA, and various industry and non-profit sponsors. I have published more than 160 articles and chapters that have been extensively cited.