Chemistry and Biochemistry
Clippinger Laboratories 249A
Education: Ph.D. University of Nebraska
Research Interest: We are interested in three research areas:
1. Radiation (UVR and IR)-induced, ROS/RNS (O2″−, OH″, NO″, ONOO− et al)-mediated regulation of translation (EIF2AK activation and eIF2 alpha phosphorylation), ER-stress, NF-kappaB activation, apoptosis and autophagy.
2. Radiation (UVR and IR)-induced, membrane raft domains-mediated redistribution/aggregation of cell surface protein, cell-cell interaction and apoptosis.
3. Identification and characterization of natural and synthetic chemicals and small peptides for chemoprevention, radio-sensitization/protection and improvement of innate immune response.