I need to submit a new study
As of February 15, 2024, all NEW studies must be submitted in Cayuse.
Cayuse HE Transition Timeline FAQ's by Submission/Study Type
Cayuse Transition Timeline FAQ's by Submission/Study Type
I have a new study submission in progress in LEO as of February 15, 2024
Studies that were fully submitted in LEO before this date (meaning all signoffs completed and in the ORC review queue by 11:59 PM EST on February 14, 2024) will continue to be processed in LEO, but they must be approved no later than March 29. If the study is not approved by March 29, you will need to resubmit the study in Cayuse. To avoid this, we request your timely responses to revision requests.
I have an existing expedited or full board study that was approved in LEO and I need to submit a periodic review
If your study expires on or after March 29, 2024, you will need to submit the study as a new study in Cayuse. These studies will be submitted and reviewed as new submissions. It will be helpful if you note the LEO IRB # as well as note any changes from the previously approved LEO protocol. Please plan to allow sufficient time for the review process to avoid a lapse in IRB approval for your study.
If your study expires before March 29, 2024, you may choose to submit a periodic review in LEO or submit as a new study in Cayuse. If you elect to stay in LEO at this time, you will need to submit the study as a new submission in Cayuse at the time of the next periodic review.
I have an existing expedited or full board study that was approved in LEO and I need to submit an amendment, protocol deviation, or adverse event
As noted above, at the time of periodic review/renewal, the study will need to be submitted as a new study in Cayuse. If your study has not expired in LEO, you may continue to submit amendments, protocol deviations, and adverse events in LEO.
I have an existing exempt study that was approved in LEO and does not expire
All exempt studies that are open and active in LEO must be submitted as a new study in Cayuse no later than April 1, 2025. If you need to submit an amendment to an exempt protocol after February 15, 2024, you will need to submit the study as a new study in Cayuse. These studies will be submitted and reviewed as new submissions.
I'm staff but submitting to the IRB as a student
In Cayuse, you will submit using your staff account, but indicate in the application form, Section 8, that the study is a student-led research project.
I have an existing study in LEO that I am ready to close
Completed studies can still be closed in LEO. The Periodic Review button has been replaced with a Close Study button.