21.0 Work With Substances of Moderate to High Chronic Toxicity or High Acute Toxicity
21.1 Use of Designated Areas
21.1.1 A designated area must be established for work with "select carcinogens", reproductive toxins, and substances, which have a high degree of chronic or acute toxicity.
21.1.2The following procedures must be developed for all work with "select carcinogens", reproductive toxins, and substances of high acute toxicity.
21.1.3 The establishment of a "designated area". This may be an entire laboratory, an area of a laboratory or a device in the laboratory, such as a hood. This area must be clearly marked.
21.1.4 Required approvals for conducting the project. i.e. Work with known carcinogens is regulated by the O.U. I.B.C. Contact the I.B.C. chair or the Biosafety Office at EHS for requirements. Others may be:
- Radiation safety committee
- Animal care committee
- Human subjects committee
21.1.5 Control equipment required, glove box, hood, etc.
21.1.6 Proper storage procedures.
21.1.7 The personal protection required.
21.1.8 The procedures for retention of records on amounts of these materials on hand and used, and the names of the workers involved.
21.1.9 Procedures for the prevention of spills and accidents, and emergency response.
21.1.10 Procedures for the prevention of spills and accidents, and emergency response.
21.1.11 (Specify the designated area in your lab and procedures for the laboratory)
21.1.12 A select few toxins are regulated by the "Anti-Terrorism and Effective Death Penalty Act" (also called the Agents Transfer Law), See EHS for list and consultation. O.U is not currently licensed for this.
21.2 Operations Requiring Prior Approval
21.2.1 Certain laboratory operations are of special concern because of the potential hazards associated with them. In these instances laboratory personnel are instructed to obtain prior approval from (specify person) prior to commencing the operation. This is to assure that safeguards are in place and that personnel are adequately trained in the procedure.
21.2.2 A departmental proposal review system is established as follows: List specific activities, procedures, or chemicals requiring prior approval from the department.
21.2.3 All proposals regulated by O.U.Radiation Safety Committee or Institutional Biosafety Committee (IBC) should be submitted as required.
21.2.4 All toxins regulated by the "Anti-Terrorism and Effective Death Penalty Act" (Agent Transfer Law). O.U. is not currently licensed for this.