College of Arts and Sciences
Heritage College of Osteopathic Medicine
Russ College of Engineering and Technology
Faculty
Ohio Expert
Erin Murphy
Chair, Biomedical Sciences; Professor of Bacteriology
Athens Campus
Biomedical Engineering
Biomedical Sciences
Infectious and Tropical Disease Institute
Molecular and Cellular Biology
Education
- Microbiology (PhD), State University of New York at Buffalo, 2002
- Biology (BS), State University of New York at Geneseo, 1997
Areas of Expertise
- Bacteriology
- Infectious Disease
- Gene Regulation
- RNA Thermometer (RNAT)
- Shigella
- Staphylococcus aureus
- Microbiology
- Small RNA (sRNA)
OHIO Expert
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Our research focuses on understanding how disease-causing bacteria regulate gene expression in response to specific environmental conditions encountered within the infected host. Focus is placed on the study of RNA-mediated gene regulation that impact the ability of bacteria to survive within the host and cause disease.
View My Work in Open Researcher and Contributor ID (ORCID)
View My Work in the National Center for Biotechnology Information (NCBI)
Journal Article, Academic Journal (17)
- Sarpong, D., Murphy, E. (2021). RNA Regulated Toxin-Antitoxin Systems in Pathogenic Bacteria. Frontiers in Cellular and Infection Microbiology.
- Bastock, R., Marino, E., Wiemels, R., Holzschu, D., Keogh, R., Zapf, R., Murphy, E., Carroll, R. (2021). Staphylococcus aureus Responds to Physiologically Relevant Temperature Changes by Altering Its Global Transcript and Protein Profile.. 2. mSphere; 6.
- Jensen, E., Young, J., Jackson, Z., Busken, J., List, E., Carroll, R., Kopchick, J., Murphy, E., Berryman, D. (2020). Growth Hormone Deficiency and Excess Alter the Gut Microbiome in Adult Male Mice.. 4. Endocrinology; 161.
- Murphy, E., Roßmanith, J., Sieg, J., Fris, M., Hussein, H., Kouse, A., Gross, K., Zeng, C., Hines, J., Narberhaus, F., Coschigano, P. (2020). Regulation of OmpA Translation and Shigella dysenteriae Virulence by an RNA Thermometer.. 3. Infection and immunity; 88.
- Jensen, E., Young, J., Mathes, S., List, E., Carroll, R., Kuhn, J., Onusko, M., Kopchick, J., Murphy, E., Berryman, D. (2020). Crosstalk between the growth hormone/insulin-like growth factor-1 axis and the gut microbiome: A new frontier for microbial endocrinology.. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society; 53-54: 101333.
- Jensen, E., Berryman, D., Murphy, E., Carroll, R., Busken, J., List, E., Broach, W. (2019). Heterogeneity spacers in 16S rDNA primers improve analysis of mouse gut microbiomes via greater nucleotide diversity.. 2. BioTechniques; 67: 55-62.
- Hussein, H., Fris, M., Salem, A., Wiemels, R., Bastock, R., Righetti, F., Burke, C., Narberhaus, F., Carroll, R., Hassan, N., Mohamed, S., Fahmy, A., Murphy, E. (2019). An unconventional RNA-based thermosensor within the 5' UTR of Staphylococcus aureus cidA.. 4. PloS one; 14: e0214521.
- Wei, Y., Kouse, A., Murphy, E. (2017). Transcriptional and posttranscriptional regulation of Shigella shuT in response to host-associated iron availability and temperature.. 3. MicrobiologyOpen; 6.
- Fris, M., Broach, W., Klim, S., Coschigano, P., Carroll, R., Caswell, C., Murphy, E. (2017). Sibling sRNA RyfA1 Influences Shigella dysenteriae Pathogenesis.. 2. Genes; 8.
- Wei, Y., Murphy, E. (2016). Shigella Iron Acquisition Systems and their Regulation.. Frontiers in cellular and infection microbiology; 6: 18.
- Fris, M., Murphy, E. (2016). Riboregulators: Fine-Tuning Virulence in Shigella.. Frontiers in cellular and infection microbiology; 6: 2.
- Caswell, C., Oglesby-Sherrouse, A., Murphy, E. (2014). Sibling rivalry: related bacterial small RNAs and their redundant and non-redundant roles.. Frontiers in cellular and infection microbiology; 4: 151.
- Kouse, A., Righetti, F., Kortmann, J., Narberhaus, F., Murphy, E. (2013). RNA-mediated thermoregulation of iron-acquisition genes in Shigella dysenteriae and pathogenic Escherichia coli.. 5. PloS one; 8: e63781.
- Oglesby-Sherrouse, A., Murphy, E. (2013). Iron-responsive bacterial small RNAs: variations on a theme.. 4. Metallomics : integrated biometal science; 5: 276-86.
- Murphy, E., Broach, W., Kouse, A. (2012). Prokaryotic Gene Regulation by Small RNAs.
- Broach, W., Egan, N., Wing, H., Payne, S., Murphy, E. (2012). VirF-independent regulation of Shigella virB transcription is mediated by the small RNA RyhB.. 6. PloS one; 7: e38592.
- Africa, L., Murphy, E., Egan, N., Wigley, A., Wing, H. (2011). The iron-responsive Fur/RyhB regulatory cascade modulates the Shigella outer membrane protease IcsP.. 11. Infection and immunity; 79: 4543-9.
Book, Chapter in Scholarly Book (1)
- Murphy, E., Broach, W., Kouse, A. (2014). Prokaryotic Gene Regulation by Small RNAs.
Abstract (1)
- Jensen, J., Jackson, J., Busken, J., Young, J., Kuhn, J., Carroll, R., List, E., Murphy, E., Kopchick, J., Berryman, D. (2019). Growth Hormone (GH) Impacts the Gut Microbial Profile: the Presence of Unique Bacterial Genera in Mouse Lines with Altered GH Action. 1. 3.