Associate Professor of Pharmacology
Biochemistry and molecular biology of signal transduction in platelets; role of methylation/demethylation and phosphorylation/ dephosphorylation of ras-related G proteins in cellular signaling.
Assistant Professor of Immunology
My research explores the capability of antigen presenting cells (dendritic cells and macrophages) to act as inducers or suppressors of immunity responses in different diseases such as cancer, atherosclerosis or infections. Investigating the factors governing the plasticity of these cells may unhide new targets for immune therapies.
Associate Professor of Microanatomy
Roles of the actin cytoskeleton in epithelial cell morphogenesis; regulation of membrane-cytoskeletal interactions; characterization of a new family of human chloride channel proteins.
Bonita J. Biegalke
Associate Professor of Microbiology
Molecular biology of herpesviruses; regulation of gene expression; mechanisms of pathogenicity.
Professor of Biochemistry
Design and study of novel antimicrobial peptides.
Associate Professor of Microbiology.
In vitro and in vivo antidiabetic and anti-obesity activities and signaling pathways of novel compounds and their use in treatment of type 1 and type 2 diabetes; anti-cancer and apoptosis-inducing activities and mechanisms of natural and synthetic compounds.
Peter W. Coschigano
Associate Professor of Environmental Microbiology
Genetics and molecular biology of microorganisms that degrade toxic compounds, regulation of gene expression, elucidation of metabolic pathways.
Karen T. Coschigano
Identification of genes involved in the development of diabetes and its complication, especially in the kidney, using molecular tools and mouse models that mimic human disease.
Mario J. Grijalva
Professor of Microbiology
Molecular diagnosis, immunology and epidemiology of Tropical diseases.
Frank M. Horodyski
Professor of Molecular Biology
Molecular biology of insect neuropeptides and their roles in development and metamorphosis.
Associate Professor of Renal Physiology
Research involves understanding the mechanisms underlying the protective role of HMG-CoA reductase inhibitors in renal transplantation and ischemia/reperfusion injury.
Calvin B. L. James
Associate Professor of Virology
Molecular biology of adenoviruses: study of those aspects of signal transduction pathways relevant to both viral and cellular gene regulation.
John J. Kopchick
Goll Ohio Eminent Scholar, Professor Molecular and Cellular Biology
We are interested in the molecular and cellular events involved in growth, obesity, and diabetes. We use transgenic and gene disrupted mice as well as genomic and proteomic approaches to study these areas. Overall we would like to determine the mechanisms that result in mammalian growth. Additionally, we would like to determine the genetic defects that result in abnormal growth phenotypes or improper meabolic function.
Assistant Professor of Specialty Medicine
Research topis: Diabetes, inflammation, autoimmune disease, tumor biology, innate immunity, small molecule therapeutics. Toll-Like receptors and their involvement in the pathogenesis and progression in cancers: thyroid, pancreatic, prostate, breast, colon and malignant melanoma.
Associate Professor of Neuroscience
Cellular and molecular mechanisms of neural transmission, plasticity, and intracellular signaling.
Assistant Professor of Pathology
Understanding how inflammation is involved in the pathogenesis of chronic disease.
Our goal is to elucidate the role of inflammation in the pathogenesis of atherosclerosis, diabetes and cancer.
Assistant Professor of Biomedical Sciences
My research focuses on understanding the regulatory mechanisms governing the expression of genes encoding bacterial virulence determinants. In particular I am interested in gene expression controlled by non-coding RNA molecules in response to environmental signals.
Felicia V. Nowak
Associate Professor of Biomedical Sciences
Gene regulation of growth factors; Transgenic models; Growth factor effects on mammalian brain development and plasticity; Effects of gender on brain development and function; Aging and neurodegeneration.
Edwin C. Rowland
Associate Professor of Immunoparasitology
Immunobiology of Trypanosoma cruzi infection in mice.