IACUC Review Routes: Know Your Options

1. New Protocols 

2. De Novo Reviews (i.e. Renewals) 

3. Amendments that do not qualify for DMR, VVC, or Admin Review 

FCR is conducted monthly during scheduled IACUC meetings. Please be sure to submit your protocol before the submission deadline.  

 You can view the current meeting schedule here “IACUC Meeting Schedule”. 

1. Amendments typically involving- 

• Change in transportation of animals  

• Change in animal numbers, sex, age/weight range, animal ID method  

• Change in animal source  

• Change in strains used  

• Change in literature search  

• Change in procedures or addition of procedures that DO NOT involve surgery, anesthesia, prolonged restraint, or special husbandry  

•  Change of housing location    

2. DMR Subsequent to FCR-  

When a protocol or amendment is reviewed via Full Committee Review (FCR), the IACUC may use Designated Member Review (DMR) to evaluate and approve required modifications needed to secure final approval. 

Typically completed within 6 business days once assigned to reviewers. 

Please note: Any IACUC member may request that a submission under DMR be elevated to Full Committee Review (FCR), which would then follow the monthly meeting schedule. 

Amendments involving- 

•  Anesthesia, analgesia, or sedation: Changes to the specific drugs or dosages are allowed only if these procedures are already approved in the protocol. The VVC process cannot be used to add anesthesia, analgesia, or sedation if they are not already part of the approved protocol. 

• Euthanasia: Changes to the method are permitted as long as the new method is listed in the current AVMA Guidelines for the Euthanasia of Animals. 

Amendments involving-  

• Fixing typos or grammar errors 

• Updating contact information 

• Changes to personnel, as long as it’s not the Principal Investigator (PI) 

• Updating the funding status (e.g. new funding or end of funding) 

We strive to complete these reviews as quickly as possible. 

For personnel changes, please note that verification of CITI training and Occupational Health Program enrollment is required. If these items are incomplete or out of date, it may delay the review process.