IACUC Policy 010: Designated Member Review (DMR) Subsequent to Full Committee Review (FCR)

1 Purpose: This policy allows the IACUC two procedures by which they can use DMR subsequent to FCR when modifications are required in order to secure approval.  

2. Policy: When all voting members of the IACUC are present at a convened meeting, the committee may vote to require modifications to secure approval and have the revised research protocol reviewed and approved by designated member review (DMR).  

• When all voting members of the IACUC are not present at the convened meeting, the quorum of members present may decide by unanimous vote to use DMR subsequent to FCR. However, any member of the IACUC may, at any time, request to see the revised protocol and/or request FCR of the protocol.  
• Required documentation: All current voting, and alternate, IACUC members have agreed in advance in writing that the quorum of members present at a convened meeting may decide by unanimous vote to use DMR subsequent to FCR when modification is needed to secure approval. However, any member of the IACUC may, at any time, request to see the revised protocol and/or request FCR of the protocol. Documentation of agreement is kept by the Office of Research Compliance.  

References:

• PHS Policy IV.C.2)- https://olaw.nih.gov/policies-laws/phs-policy.htm#ReviewofPHS-Conducted…
• Guidance to IACUCs Regarding Use of Designated Member Review (DMR) for Animal Study Proposal Review Subsequent to Full Committee Review (FCR)- https://grants.nih.gov/grants/guide/notice-files/NOT-OD-09-035.html