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Completed Projects

The following studies have been closed for enrollment.

Please contact the CTRU with any questions.

HITFIT: Feasibility of High Intensity Interval Training in Adolescent Populations with Obesity (Emily Guseman, PhD)
Researchers at Ohio University are studying exercise preferences and performance among teenage boys and girls whose weight is higher than it should be. Children are eligible to participate if they are 14 to 18 years old at the time of enrollment, meet weight criteria, can exercise safely, are not currently participating in an organized sport and are not pregnant. Participation in the study will last six weeks, including assessments at the beginning and end and four weeks of supervised exercise (three times weekly). Participants will be compensated for their time and effort.

Assessment of toddlers' lifestyle behaviors and related parenting practices (Emily Guseman, PhD)
Researchers want to know how our behaviors and habits influence child growth. This study is seeking to measure how a child’s activity and sleep compare to current recommendations. Participants should be children ages 2-5 years who can walk by themselves, with a primary caregiver between the ages of 18-55. Participants should be willing to attend one study visit with their child and attend one additional visit alone. Compensation will be provided.

Using Yoga to Reduce Chaos and Improve Preschooler Sleep (Emily Guseman, PhD)
This study is looking at preschoolers' bedtime routines. Participants need to not be pregnant at the time of participation, and children must be between the ages of 2 and 5.

PROMINENT: Pemafibrate to Reduce cardiovascular OutcoMes by reducing triglycerides IN diabetic patiENTs (Vipin Koshal, DO, FACC)
This study is a Phase 3, randomized, double-blind, placebo-controlled, international trial evaluating the ability of an investigational product to prevent cardiovascular events among adults with type 2 diabetes and high levels of triglycerides with a history of statin therapy. The study is seeking males over the age of 50 and females over the age of 55 who meet study inclusion criteria. The total expected treatment duration is up to five years, with an expected average follow-up period of approximately four years. Qualified volunteers may receive compensation.

Kids Body Comp Study (Cheryl Howe, PhD)
Do you want to know your child’s bone density, body fat percentage and their health and fitness level? To participate, your child must be 7 to 17 years of age, with no metal implants and not currently or possibly pregnant. They must also be less than 450 pounds and have had no CT, barium or radio-isotope procedure within the past seven days. To participate in all three parts, your child must not have any physical, metabolic, respiratory or neurological impairments that would affect their ability to exercise for three minutes safely.

Seasonal Variation in Children's Lifestyle Behaviors during the COVID-19 Pandemic (Emily Guseman, PhD)
Are you the parent/guardian of a child between the ages of 6-17? Ohio University researchers are studying children’s behavior during COVID (IRB # 20-E-322).

Women's experience of smoking exposure in pregnancy (Ilana Chertok, PhD)
We want to learn about your experience with smoking exposure during pregnancy. We are looking for healthy pregnant women, aged 18 or older, who are exposed to smoking at home.

Survey for Ohio Older Adults (Taylor Lambertus, Julie Suhr, PhD)
Adults aged 50 or older living in Ohio are needed for an anonymous survey study. Participants will be asked about concerns regarding aging and dementia and about interest in potentially participating in a virtual educational intervention about healthy aging, dementia and what you can do to prevent dementia. The survey will take approximately 30 minutes. This research study will be conducted through Ohio University.

OMT Effects On Post-Covid19 Anosmia/Hyposmia (Michael Stenta, OMS-IV)
A research team through Ohio University Heritage College of Osteopathic Medicine is working to return or increase sense after COVID-19 illness. You must be 18 years of age or older, have  documentation of a positive COVID-19 test, have loss of sense of smell during your COVID-19 illness and still be experiencing diminished smell.

Understanding Nurse Turnover: The Cyclical Role of Understaffing (Mohsin Sultan, MS; Ryan Johnson, PhD)
Are you currently working full time in the nursing profession? Ohio University researchers are recruiting full-time nurses to participate in a study about their work and non-work experiences. To participate, you must be 18 years of age or older, live in the United States, be able to read and write in English and be employed as part of a larger organization (e.g., hospital, nursing home, rehabilitation center) where you regularly work with other nurses (i.e., independent in-home care nurses are not eligible).

The DART Study: Exercise Strategies to Improve Physical Function in Older Adults (Dallin Tavoian, PhD Candidate)
This study is looking for individuals between 60 and 75, not living in a nursing home or assisted living facility, who are interested in participating in an exercise-based research study. Help researchers better understand the health effects of different exercise strategies.

Sleep and Cognition in Older Adults (Julie Suhr, PhD)
This study will examine how sleep affects cognitive abilities in older adults. This study is seeking participants 50 years of age and older with concern about their sleep and cognitive abilities. If you participate, you will complete several self-report measures examining sleep habits, medical and psychological history, and your perceptions of your cognitive abilities. You will also complete a brief battery of cognitive tests. The entire study should take about two hours to complete. 

The BONE Study: Older Adult Perception of Cortical Bone Mechanics Technology Testing Procedure (Anne Loucks, PhD)
This study is seeking participants aged 50-99 to participate in a research study to improve a new technology for assessing bone health. Participants must not be living in a nursing home or assisted living facility, must have at least one arm that has not suffered a fracture or other musculoskeletal or orthopedic injury within the past year and be willing to complete three laboratory-based testing sessions (6 hours total). Eligible participants will be compensated for their time.

Safety and Efficacy of BIO-101 175 mg b.i.d. and 350 mg b.i.d. 26-week oral administration to patients suffering from age-related SARcopenia, including sarcopenic obesity, Aged 65 years and at risk of mobility disability. A double-blind, placebo control (Brian Clark, PhD)
This study is  looking for participants over the age of 65 who report a loss of physical function and are considered at risk of mobility disability. 

Achieving a High Level of Wellness by Focusing on the Impact of Diabetes Distress in Rural Appalachia (Liz Beverly, PhD)  
This study is being done to learn about behavioral and emotional challenges to living with diabetes in southeastern Ohio. Participants will be asked to complete a demographic form and six surveys about your diabetes and well-being. To be eligible, you must have type 1 or type 2 diabetes, be aged 18 years or older and able to read and speak English, and live in southeastern Appalachian Ohio (Athens, Hocking, Meigs, Morgan, Perry, Vinton, Washington counties). Compensation will be provided.

Reboot Study (David Drozek, DO)
This is a randomized, controlled / comparison study that will evaluate the effectiveness of WellStart, a virtual intensive therapeutic lifestyle change program to control type 2 diabetes.

Intelligent Decision Support for Type I Diabetics on Insulin Pump Therapy and Real-Time Continuous Glucose Monitoring IV (Cynthia Marling, PhD)
Seeking patients from the University Medical Associates Diabetes/Endocrine Center in Athens, Ohio, or the Camden Clark Medical Center for Diabetes and Endocrine Diseases in Parkersburg, West Virginia, with Type 1 Diabetes Mellitus and who are already on insulin pump therapy. Subjects must be at least 14 years of age with internet access on a computer and smartphone.

The UNCODE Study (Unraveling the Neural Contributors Of Dynapenia in Elders) (Brian Clark, PhD)
This study seeks to better identify the neurological causes of muscle weakness associated with aging. Additionally, it will examine the potential for different interventional strategies to enhance muscle and physical performance. The UNCODE Study is being conducted by scientists at the Ohio Musculoskeletal and Neurological Institute at Ohio University. Please visit to stay up-to-date on study results.

A Phase 1b Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects with Limitations in Mobility (Brian Clark, PhD)
This study is seeking adults between the ages of 70 and 89 years old to help evaluate the effect of an investigational medication on muscle fatigue and physical function in mobility-limited older adults. To be eligible, you must be able to write in English, attend study visits at Ohio University, be living at home, have some limitations in physical function and mobility, and not have had a cardiac event within the last six months. Qualified volunteers may receive compensation.

Preliminary Validation of the Physical Activity Impact Scale (PAISs): Primary Data Collection Study (Brian Clark, PhD)
This study will be seeking participants 70 years of age or older who weigh at least 88 lbs. Participants should be willing to complete a walk test and scan of body composition, as well as complete surveys on an electronic tablet such as an iPad or tablet.

Innovative Imaging of Cerebrum and Muscle (iCAM) Pilot (Brian Clark, PhD)
This study is looking for males and females aged 18+ with no significant health issues to participant in pilot testing experiments. These testing experiments are to develop muscle functional magnetic resonance imaging and functional magnetic resonance imaging techniques to study the neural control of the truck muscles.

Cardiovascular Inflammation Reduction Trial (CIRT) (Vipin Koshal, DO, FACC)
A randomized, double-blind, placebo-controlled, event-driven trial of weekly low-dose methotrexate in the prevention of cardiovascular events among stable coronary artery disease patients with Type 2 diabetes or metabolic syndrome. The CIRT trial is seeking participants over the age of 18 with Type 2 diabetes or metabolic syndrome and a history of a cardiovascular event. Please visit to stay up-to-date on study results.

Lifestyle Change and Body Composition: a Pilot Study (David Drozek, DO)
This study is looking for adults 18 years of age or older who are enrolled in the Complete Healthy Improvement Program, with a BMI higher than 25 and who are able to speak, read and write in English.

Examining Cognitive Effort during Language Processing (Laura Roche Chapman, MA, CCC-SLP)
The Ohio University Neurolinguistics Laboratory is seeking participants aged 18-89 to participate in a study designed to look at the amount of effort individuals need to comprehend different types of sentences using pupil dilation and constriction. Participants must be native speakers of American English with no history of stroke or brain injury. The study involves a one-time visit to Grover Center on Ohio University’s Athens campus lasting approximately one hour. Participants will receive $10 cash upon completion of all parts of the study.

TMAO and a Plant-Based Diet: a Pilot Study (David Drozek, DO)
The aim of this study is to determine if eating two whole, hard-boiled brown eggs daily for 29 days will increase production of trimethylamine N-oxide, a marker of plaque buildup in artery walls, in people who normally eat a vegan/totally plant-based diet. The results of this marker will be taken from blood tests. If you agree to participate in the study, you will be assigned to one of two groups based on your previous two-month diet: the plant-based group agreeing to eat two whole, hard-boiled brown eggs daily or the animal-based diet group.

An Office-based Small Group Lifestyle Medicine Program: a Pilot Study (David Drozek, DO)
This study is looking for non-pregnant adults who participate in The Lifestyle Medicine Clinic: Small Group. Combined with community-based small group to create "Lifestyle Changes and Body Composition: a Pilot Study."

A Community-based Small Group Lifestyle Medicine Program: a Pilot Study (David Drozek, DO)
This study is looking for non-pregnant adults 18 to 80 years of age who are able to fast for lab work, attend at least four of the six session of the community-led version of The Lifestyle Medicine Clinic: Small Group. Combined with office-based small group to create "Lifestyle Changes and Body Composition: a Pilot Study."

Zanfel® vs. Prednisone/Diphenhydramine for Contact Dermatitis as a Result of Exposure to Toxidendron (Poison Ivy, Poison Sumac, or Poison Oak) (Todd Fredricks, DO)
This study will be help military pre-deployment personnel during 2016 trainings at Ravenna Joint Military Training Center in Paris, Ohio. Potential participants who present for medical care for contact dermatitis as a result of exposure to poison ivy, poison sumac or poison oak will be identified and presented with the study information and option to consent to participate.

The RELIEF Study - Researching the Effectiveness of Lumbar Interventions for Enhancing Function (James Thomas, PhD, PT)
The RELIEF Study is seeking men and women between the ages of 18-45 years to participate in a research study investigating treatment for low back pain. Participation requires completing several testing sessions and attending several intervention sessions. Financial compensation is provided for participating in this study. Please call 740.566.7246 (PAIN) for more information. Please visit to stay up-to-date on study results.

BEND: Back Exercises to Neutralize Disability (Brian Clark, PhD)
Seeking participants aged 18 to 50 years with two or more episodes of low back pain in the past 12 months, with at least one of the episodes causing a restriction of work or leisure time activity. Please visit to stay up-to-date on study results.

Effect of a Plant-based, Low Fat Diet on Gallstones (David Drozek, DO)
This study is seeking participants between the ages of 21 and 80 years who continue to have their gallbladder and who are enrolled in either the CHIP program or Lifestyle Medicine Clinic, or willing to enroll in either of these programs.

Effectiveness of Replacing Run Training with ElliptiGO Training Over 4-Weeks in Experienced Runners (Ian Klein, MS)
This study is seeking experienced runners between 18-35 years old to participate in a four-week exercise training program using an ElliptiGO bike. Specifically, investigators will aim to better understand the fitness and performance effects of replacing 50% of your run training with ElliptiGO training. Participants will be able to train on a new piece of exercise equipment, the ElliptiGO, which is a fast-growing piece of exercise equipment that could aid in the optimization of a runner's training.

Assessing the Reliability of the Use of a Novel Imaging and Modeling Technique in Quantification of Spine Motion in Humans (Spine Motion Study) (Niladri Mahato, PhD)
This study is looking for healthy subject between 18-60 years of age without current back pain, with no history of spine surgeries, no history of heart disease or low blood pressure, or current use of pain medication or supplements, and with no major depression.

A Longitudinal Assessment of Osteopathic Medical Students' Physical Health (Zachary Glenn, DO Candidate)
This study is looking for current first- and second-year Heritage College students at the Athens campus.

A Multicenter Study Conducted to Evaluate the Performance of the Mesa Biotech Flu A/Flu B Test in Laboratory and Point of Care Testing Sites (Timothy Law, DO)
This study is looking for subjects 18 years or older with a preliminary assessment that exhibits two or more signs and symptoms that may be caused by the influenza virus.

Impact of Lifestyle Changes via The Lifestyle Medicine Clinic on Women and Daughters (David Drozek, DO)
This study is looking for daughters between the ages of 12-18 years and their mothers, who will enroll in The Lifestyle Medicine Clinic.

Metabolic Disease in a Developmental Context: Does Childhood Stress Affect Your Risk for Chronic Disease? (Anne Farbman, Gillian Ice, PhD, MPH)
This study is seeking females between the ages of 40-55 years who currently reside in Athens, Hocking, Meigs, Morgan, Perry or Washington counties in Ohio.

LEARNING: Lumbar Extension Activities Reinforced through Novel Interactive Gaming (James Thomas, PhD, PT)
The purpose of The LEARNING Study is to measure the effects of an interactive, whole-body video game on movement behavior in people with low back pain. Currently recruiting participants age 18-50 with chronic low back pain symptoms for at least the past three months.

Long-Term Experience with Insulin First and INSPIRE Programs (Elizabeth Beverly, PhD)
This study will be seeking past participants of the Insulin First and INSPIRE protocols to follow up about their experiences in these trials, lifestyle changes and their beliefs about diabetes, attitudes toward insulin and diabetes care.


Contact Us

Clinical & Translational Research Unit
230 Irvine Hall
Athens, OH 45701
Phone: 740.566.9873 | Fax: 740.566.9874
Facebook: @OhioUniversityCTRU