NHGRI funds BME faculty member’s bioinformatics work on cancer tissue analysis
Nov. 25, 2009
Lonnie Welch, Stuckey Professor of Electrical Engineering and Computer Science and member of the biomedical engineering program faculty, is the principal investigator on a project that is funded by the National Human Genome Research Institute (of the National Institutes of Health).
The contract of $36,000 will be used by the Ohio University Bioinformatics Laboratory (OUBL) to develop a pipeline to analyze DNA methylation data from cancer tissue samples. The hypothesis is that late stage tumor cells have DNA methylation patterns that differ from those of normal cells. To test the hypothesis, the OUBL is developing a bioinformatics pipeline to determine which genomic regions have statistically significant changes. This is being applied to several types of cancer cells and is being used to identify genes that are associated with cancer.