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A Diabetes-Free Society

Director, Basic and Applied Research

CoschiganoKaren T. Coschigano, PhD
Associate Professor, Molecular/Cellular Biology
Department of Biomedical Sciences
Heritage College of Osteopathic Medicine

Dr. Karen T. Coschigano, is an associate professor of molecular/cellular biology at the Ohio University Heritage College of Osteopathic Medicine (OU-HCOM) in the Department of Biomedical Sciences. She received her doctoral degree in biochemistry from Brandeis University in 1992 and completed postdoctoral training in transcriptional regulation at New York University and in molecular endocrinology at Ohio University. Her current research is geared toward elucidating the molecular mechanisms of diabetic nephropathy using mouse models.

Academically, Dr. Coschigano is involved in curricular administration and lecturing to first and second year medical students. In the research laboratory, she mentors undergraduate, graduate and medical students, teaching them how to ask and answer research questions and providing them with opportunities for independent research.

Dr. Coschigano is actively involved in several research initiatives. One research focus is the role of two transcription factors, signal transducer and activator of transcription 5 a and b (STAT5 a and b) in the pathogenesis of diabetes and inflammation within the kidney. She is also investigating the role of growth hormone signaling in diabetic nephropathy. For each project she utilizes experimentally induced diabetes and mouse models with altered expression of the genes of interest. Her research combines both in vitro and in vivo methodology in order to study individual molecules and observe intact organ responses.

Dr. Coschigano's office is in Academic & Research Center 302d. You can reach her by email at