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Member Profile


Darlene  Berryman, PhD, RD, LD

Professor, Nutrition

CHSP / HCOM / EBI 

Konneker 108 

740-593-9961

Member Type: Investigator 

Research Interest

The unifying theme of my scholarly work is obesity. I am fortunate to be able to address this timely subject from two different perspectives, mainly as a basic scientist but occasionally as a clinician. The majority of my scholarly efforts are to assess the nutritional and hormonal factors that impact adipose (fat) tissue and influence risk of obesity as well as its associated diseases. More specifically, I investigate how growth hormone (GH) levels and diets with various macronutrient profiles impact adipose tissue distribution, metabolism, and function as well as the progression of obesity to overt diabetes. Because GH and diet also have been shown to manipulate longevity, I am interested in how these factors influence aging. 

Complete Curriculum Vitae (PDF)

Selected Publications

Benencia, F., Harshman, S., Duran-Ortiz, S., Lubbers, E. R., List, E. O., Householder, L., … Berryman, D. E. (2015). Male bovine GH transgenic mice have decreased adiposity with an adipose depot-specific increase in immune cell populations. Endocrinology, 156(5), 1794–1803. http://doi.org/10.1210/en.2014-1794
***Highlighted in seperate commentary of this issue: Odle et al, Endocrinology, 156(5), pp. 1611-1612***

List, E. O., Berryman, D. E., Funk, K., Gosney, E. S., Jara, A., Kelder, B., … Kopchick, J. J. (2013). The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice. Molecular Endocrinology (Baltimore, Md.), 27(3), 524–535. http://doi.org/10.1210/me.2012-1330

Lubbers, E. R., List, E. O., Jara, A., Sackman-Sala, L., Cordoba-Chacon, J., Gahete, M. D., … Berryman, D. E. (2013). Adiponectin in mice with altered GH action: links to insulin sensitivity and longevity? The Journal of Endocrinology, 216(3), 363–374. http://doi.org/10.1530/JOE-12-0505

List, E. O., Berryman, D. E., Wright-Piekarski, J., Jara, A., Funk, K., & Kopchick, J. J. (2013). The effects of weight cycling on lifespan in male C57BL/6J mice. International Journal of Obesity (2005), 37(8), 1088–1094. http://doi.org/10.1038/ijo.2012.203

Berryman, D. E., List, E. O., Sackmann-Sala, L., Lubbers, E., Munn, R., & Kopchick, J. J. (2011). Growth hormone and adipose tissue: beyond the adipocyte. Growth Hormone & IGF Research: Official Journal of the Growth Hormone Research Society and the International IGF Research Society, 21(3), 113–123. http://doi.org/10.1016/j.ghir.2011.03.002
***Noted as one of the most downloaded articles from this journal in 2012***

Berryman, D. E., List, E. O., Palmer, A. J., Chung, M.-Y., Wright-Piekarski, J., Lubbers, E., … Kopchick, J. J. (2010). Two-year body composition analyses of long-lived GHR null mice. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 65(1), 31–40. http://doi.org/10.1093/gerona/glp175

Berryman, D. E., Christiansen, J. S., Johannsson, G., Thorner, M. O., & Kopchick, J. J. (2008). Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models. Growth Hormone & IGF Research: Official Journal of the Growth Hormone Research Society and the International IGF Research Society, 18(6), 455–471. http://doi.org/10.1016/j.ghir.2008.05.005

Berryman, D. E., List, E. O., Coschigano, K. T., Behar, K., Kim, J. K., & Kopchick, J. J. (2004). Comparing adiposity profiles in three mouse models with altered GH signaling. Growth Hormone & IGF Research: Official Journal of the Growth Hormone Research Society and the International IGF Research Society, 14(4), 309–318. http://doi.org/10.1016/j.ghir.2004.02.005

For more publications please link to PubMed.

Awards and Honors

2011-2012        Honors Tutorial College Distinguished Mentor Award,
                          Honors Tutorial College, Ohio University
2010                 Outstanding Research and Creativity Award,
                          College of Health Sciences and Professions, Ohio University
2010                 Lee Cibrowski Mentor Award,
                          College of Health Sciences and Human Services, Ohio University

 

Related Links

WOUB Media-OU Professor Dispels Obesity Myths
Lab Lessons-A Life in Research
WOUB Media-OU Certificate To Tackle Diabetes

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