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Eric Masson
181 Clippinger Laboratories
740-593-0148 (Fax)

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Associate Professor
Ph.D. Swiss Federal Institute of Technology (EPFL),
Lausanne, Switzerland

Bioorganic and Supramolecular Chemistry


Research in the Masson group is very interdisciplinary, with supramolecular chemistry being the core of our research, from which a wide range of fields radiates. Examples include physical organic, synthetic, bioorganic and medicinal chemistry, as well as material science. We are particularly interested in the recognition properties of the cucurbit[n]uril hosts, a family of macrocycles which display extreme affinity towards a wide set of guests, and can be incorporated into various molecular machines. Applications we can foresee include supramolecular catalysis, controlled drug release, and the design of stimuli-responsive nanomaterials.

Selected Publications

Joseph, R.; Masson, E. “Atropisomerization in Confined Space; Cucurbiturils as Tools to Determine the Torsional Barrier of Substituted Biphenyls”, Eur. J. Org. Chem. 2014, 105 – 110.

Joseph, R.; Masson, E. “Subtle "supramolecular buttressing effects" in Cucurbit[7]uril/guest assemblies”, Org. Biomol. Chem. 2013, 11, 3116 – 3127.

Masson, E. “Torsional barriers of substituted biphenyls calculated using density functional theory: a benchmarking study”, Org. Biomol. Chem. 2013, 11, 2859 – 2871.

Ling, X.; Masson, E. “Cucurbituril Slippage: Cations as Supramolecular Lubricants”, Org. Lett. 2012, 14, 4866 – 4869.

Masson, E.; Ling, X.; Joseph, R.; Kyeremeh-Mensah, L.; Lu, X. “Cucurbituril Chemistry: a tale of supramolecular success”, RSC Adv. 2012, 2, 1213 – 1247.

Masson, E.; Shaker, Y. M.; Masson, J. P.; Kordesch, M. E.; Yuwono, C. “'Supramolecular Circuitry’: Three Chemiluminescent, Cucurbit[7]uril-Controlled On/Off Switches”, Org. Lett. 2011, 13, 3872 – 3875.

Lu, X.; Masson, E. “Formation and Stabilization of Silver Nanoparticles with Cucurbit[n]urils (n = 5−8) and Cucurbituril-Based Pseudorotaxanes in Aqueous Medium”, Langmuir>/i> 2011, 27, 3051 – 3058.

Ling, X.; Samuel, E. L.; Patchell, D. L.; Masson, E. “Cucurbituril Slippage: Translation is a Complex Motion”, Org. Lett. 2010, 12, 2730 – 2733.

Lu, X.; Masson, E. “Silver-Promoted Desilylation Catalyzed by Ortho- and Allosteric Cucurbiturils”, Org. Lett. 2010, 12, 2310 – 2313.

Masson, E.; Lu, X.; Ling, X.; Patchell, D. L. “Kinetic vs Thermodynamic Self-Sorting of Cucurbit[6]uril, Cucurbit[7]uril, and a Spermine Derivative”, Org. Lett. 2009, 11, 3798 – 3801.