Shiyong Wu, Ph.D.
Professor-Department of Chemistry and Biochemistry
Principal Investigator-Edison Biotechnology Institute
Member-Molecular & Cellular Biology Program
Konneker Research Labs, The Ridges
Ohio University, Athens, OH
We are interested in three research areas:
1. Radiation (UVR and IR)-induced, ROS/RNS (O2•−, OH•, NO•, ONOO− et al)-mediated regulation of translation (EIF2AK activation and eIF2 alpha phosphorylation), ER-stress, NF-kappaB activation, apoptosis and autophagy.
2. Radiation (UVR and IR)-induced, membrane raft domains-mediated redistribution/aggregation of cell surface protein, cell-cell interaction and apoptosis.
3. Identification and characterization of natural and synthetic chemicals and small peptides for chemoprevention, radio-sensitization/protection and improvement of innate immune response.
Shiyong Wu Last modified: November, 2011