Shiyong Wu, Ph.D.

Professor-Department of Chemistry and Biochemistry

Principal Investigator-Edison Biotechnology Institute

Member-Molecular & Cellular Biology Program

Konneker Research Labs, The Ridges

Ohio University, Athens, OH

We are interested in three research areas:

1. Radiation (UVR and IR)-induced, ROS/RNS (O₂^•−, OH^•, NO^•, ONOO⁻ et al)-mediated regulation of translation (EIF2AK activation and eIF2 alpha phosphorylation), ER-stress, NF-kappaB activation, apoptosis and autophagy.

2. Radiation (UVR and IR)-induced, membrane raft domains-mediated redistribution/aggregation of cell surface protein, cell-cell interaction and apoptosis.

3. Identification and characterization of natural and synthetic chemicals and small peptides for chemoprevention, radio-sensitization/protection and improvement of innate immune response.

Shiyong Wu                                                                                                                                                                   Last modified: November, 2011