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Faculty Research Index by Department

Departments/Institutes Learn about faculty research in the following departments and institutes that comprise the MCB program.



Department Of Biological Sciences
Department Of Chemistry And Biochemistry
Department Of Environmental And Plant Biology
Department of Biomedical Sciences
Department of Chemical and Biomolecular Engineering
Edison Biotechnology Institute (EBI)
Tropical Disease Institute
Diabetes Institute
Bioinformatics

 

College of Arts and Sciences


Department of Biological Sciences

 

Thierry Charlier
Assistant Professor of Biological Sciences

Cell phenotypes and molecular pathways linked to reproductive and aggressive behaviors, following testosterone challenge.

Shawn Chen
Assistant Professor of Molecular Biology/Biochemistry

The biogenesis and functions of non-coding RNAs; the mechanisms of RNA-protein interaction and RNA-ligand interaction. We are creating new approaches using biochemical, molecular biological, bioinformatic and genetic methods to discover and analyze novel functions of ncRNAs in pathogens, industrial micro-organisms and tumor cells.

Robert A. Colvin
Professor of Biological Sciences

Zinc and Calcium transport in neurons; mechanisms of neural degeneration in Alzheimer's disease and stroke; receptor-ligand interactions.

Lisa Crockett
Professor of Physiology

Physiological and biochemical adaptation, metabolism, biological membranes.

Janet S. Duerr
Associate Professor of Biological Sciences

Use a simple model organism, the nematode C. elegans, to study the roles of dopamine and other neurotransmitters in behavior. Use genetics and molecular biology to examine protein and neurotransmitter trafficking at synapses.

Donald L. Holzschu
Associate Professor of Biological Sciences

We are studying skin tumors of walleye fish that appear and completely regress on a seasonal basis. These tumors are caused by a unique group of retroviruses. Currently we are investigating the properties of viral proteins as they pertain to cell proliferation (tumor development) and cell death (tumor regression).

Shawn Kuchta
Assistant Professor of Biological Sciences

Integrate population genetics, phylogeography, and phylogenetics to study the evolution of biodiversity, including species formation, biogeography, natural selection, and taxonomy.  Current studies focus with salamanders, turtles, and damselflies.

Daewoo Lee
Associate Professor of Biological Sciences

Functional dissection of molecular elements mediating central synaptic transmission in Drosophila. Molecular and cellular bases of neuromodulation and synaptic plasticity. Mechanisms of selective dopaminergic cell loss in Parkinson's disease.

Tomohiko Sugiyama
Associate Professor of Biological Sciences

Biochemical study of DNA recombination: Meiotic recombination and DNA double-strand-break repair.

Soichi Tanda
Associate Professor of Genetics and Developmental Biology

Gene regulation and signal transduction during Drosophila development; Drosophila hamatopoiesis; biological functions of pre-mRNA secondary structures.

Matthew M. White
Professor of Ecology

Evolutionary genetics, fisheries genetics, conservation genetics, molecular systematics of fishes.


Department of Chemistry and Biochemistry

Michael Held
Assistant Professor Chemistry and Biochemistry

The biochemistry of plant cell wall biosynthesis; Vesicle trafficking of nascent plant cell wall cargo; Plant cell walls as sources of lignocellulosic bioenergy feedstocks.

Jennifer V. Hines
Professor of Organic Chemistry

Structural biology and medicinal chemistry of nucleic acids: RNA as a therapeutic target for the treatment of cancer as well as viral and bacterial infections.

Marcia J. Kieliszewski
Professor of Biochemistry

Hydroxyproline-rich glycoproteins (HRGP) of the plant extracellular matrix are implicated in all aspects of plant growth and development. We aim to elucidate the functions of these glycoproteins at a molecular level. Our experimental approach involves HRGP design by the use of synthetic genes followed by the isolation and structural/functional characterization of the transgene products.

Mark McMills
Associate Professor of Chemistry

Synthesis of bioactive natural products; development of novel synthetic methodology.

Tadeusz Malinski
Marvin & Ann Dilley White Professor of Analytical Chemistry

Biological and medical nanosensors. Nitric oxide signaling in the vasculature. Ischemia/reperfusion injury. The role of superoxide and peroxynitrite in Parkinson and Alzheimer disease, aging of cardiovascular system, arteriosclerosis and diabetes.

Shiyong Wu
Professor of Chemistry and Biochemistry

Regulation of eukaryotic protein synthesis initiation and endoplasmic reticulum (ER)-stress. Molecular mediators of UV-induced apoptosis. Natural biological therapeutics for infectious diseases and cancer therapy.

School of Electrical Engineering and Computer Science


Department of Environmental and Plant Biology

                

Harvey E. Ballard Jr.
Associate Professor of Plant Molecular Systematics and Evolution.

Molecular phylogenetic relationships of populations, species and genera, especially in the Violet family; molecular data in conservation genetics, adaptive radiation and speciation processes.

Ahmed Faik
Professor of Plant Biology

Study of plant cell wall polysaccharides biosynthesis and metabolism using functional genomics approaches (Bioinformatics, Genomics, Biochemistry, Molecular Biology)

Allan M. Showalter
Professor of Plant Molecular Biology

Molecular biology and biochemistry of hydroxyproline-rich glycoproteins in plant cell walls; structure and function of arabinogalactan-proteins; molecular adaptations of halophytes to saline environments.

Morgan L. Vis
Professor of Environmental and Plant Biology

Molecular systematics and population biology of freshwater algae.


Sarah E. Wyatt

Associate Professor of Environmental and Plant Biology

Plant growth and development with an emphasis on the use of molecular and genetic tools to study plant responses to environmental stimuli.


College of Health Sciences and Professions


School of Applied Health and Wellness


Darlene E. Berryman, Ph.D., RD, LD
Executive Director of the Diabetes Institute
HCOM Biomedical Sciences
Professor, School of Applied Health Sciences and Wellness

Depot-specific differences in adipose tissue biology; impact of growth hormone on adipose tissue; nutrient and endocrine interplay in obesity and type 2 diabetes.

 

Heritage College of Osteopathic Medicine


Department of Biomedical Sciences

 

Huzoor Akbar
Associate Professor of Pharmacology

Biochemistry and molecular biology of signal transduction in platelets; role of methylation/demethylation and phosphorylation/ dephosphorylation of ras-related G proteins in cellular signaling.

Fabian Benencia
Associate Professor of Immunology

My research explores the capability of antigen presenting cells (dendritic cells and macrophages) to act as inducers or suppressors of immunity responses in different diseases such as cancer, atherosclerosis or infections. Investigating the factors governing the plasticity of these cells may unhide new targets for immune therapies.

Mark Berryman
Associate Professor of Microanatomy

Roles of the actin cytoskeleton in epithelial cell morphogenesis; regulation of membrane-cytoskeletal interactions; characterization of a new family of human chloride channel proteins.

Bonita J. Biegalke
Associate Professor of Microbiology

Molecular biology of herpesviruses; regulation of gene expression; mechanisms of pathogenicity.

Jack Blazyk
Professor of Biochemistry

Design and study of novel antimicrobial peptides.

Xiaozhuo Chen
Associate Professor of Microbiology.

In vitro and in vivo antidiabetic and anti-obesity activities and signaling pathways of novel compounds and their use in treatment of type 1 and type 2 diabetes; anti-cancer and apoptosis-inducing activities and mechanisms of natural and synthetic compounds.

Peter W. Coschigano
Associate Professor of Environmental Microbiology

Genetics and molecular biology of microorganisms that degrade toxic compounds, regulation of gene expression, elucidation of metabolic pathways.

Karen T. Coschigano
Associate Professor

Identification of genes involved in the development of diabetes and its complication, especially in the kidney, using molecular tools and mouse models that mimic human disease.

Mario J. Grijalva
Professor of Microbiology

Molecular diagnosis, immunology and epidemiology of Tropical diseases.

Frank M. Horodyski
Professor of Molecular Biology

Molecular biology of insect neuropeptides and their roles in development and metamorphosis.

Sharon Inman
Associate Professor of Renal Physiology

Research involves understanding the mechanisms underlying the protective role of HMG-CoA reductase inhibitors in renal transplantation and ischemia/reperfusion injury.

Calvin  James
Associate Professor of Virology

Molecular biology of adenoviruses: study of those aspects of signal transduction pathways relevant to both viral and cellular gene regulation.


John J. Kopchick

Goll Ohio Eminent Scholar, Professor Molecular and Cellular Biology

We are interested in the molecular and cellular events involved in growth, obesity, and diabetes. We use transgenic and gene disrupted mice as well as genomic and proteomic approaches to study these areas. Overall we would like to determine the mechanisms that result in mammalian growth. Additionally, we would like to determine the genetic defects that result in abnormal growth phenotypes or improper meabolic function


Yang Li
Professor of Neuroscience

Cellular and molecular mechanisms of neural transmission, plasticity, and intracellular signaling.

Ramiro Malgor
Associate Professor of Pathology

Understanding how inflammation is involved in the pathogenesis of chronic disease.
Our goal is to elucidate the role of inflammation in the pathogenesis of atherosclerosis, diabetes and cancer.

Erin Murphy
Assistant Professor of Biomedical Sciences

My research focuses on understanding the regulatory mechanisms governing the expression of genes encoding bacterial virulence determinants. In particular I am interested in gene expression controlled by non-coding RNA molecules in response to environmental signals.

Felicia V. Nowak
Associate Professor of Biomedical Sciences

Gene regulation of growth factors; Transgenic models; Growth factor effects on mammalian brain development and plasticity; Effects of gender on brain development and function; Aging and neurodegeneration.


Department of Specialty Medicine

Kelly McCall
Assistant Professor of Specialty Medicine

Research topis: Diabetes, inflammation, autoimmune disease, tumor biology, innate immunity, small molecule therapeutics.  Toll-Like receptors and their involvement in the pathogenesis and progression in cancers: thyroid, pancreatic, prostate, breast, colon and malignant melanoma.

 

Russ College of Engineering and Technology


Department of Biomedical Engineering, Electrical Engineering and Computer Science

 

Lonnie Welch
Stuckey Professor, Biomedical Engineering , Electrical Engineering and Computer Sciences
Bioinformatics Computational regulatory genomics Machine learning Hih performance computing
Bioinformatics Laboratory


Department of Chemical and Biomolecular Engineering, Biomedical Engineering

Monica Burdick
Assistant Professor, Chemical and Biomolecular Engineering
Glycoconjugate mediators of cell trafficking in cancer metastasis.  Biochemical and biophysical regulation of cancer stem cell phenotype.  Adhesion of tumor cells to endothelium and vascular cells under hydrodynamic shear stress.

Doug Goetz
Professor of Chemical and Biomolecular Engineering

Dr. Goetz does research in biomedical engineering. His area of expertise is cell to cell adhesion with an emphasis on adhesion events that occur in the circulation.

Tingyue Gu
 Professor of Chemical and Biomolecular Engineering

Preparative and large-scale purification of recombinant proteins; dynamics of liquid chromatography; fermentation.