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Health Topics: Contraception: Depo-Provera

For information about receiving prescription contraceptives at Hudson Health Center, click here.

Depo-Provera is an injectable form of contraception (that is, it is given as a shot) that protects you against pregnancy for a full 3 months.  Its active ingredient is a chemical similar to progesterone that is produced by the ovaries during the second half of the menstrual cycle.  A doctor prescribes Depo-Provera, but a doctor, nurse or other health care provider may give the injection.

Depo-Provera acts by preventing egg cells from ripening.  If an egg is not released from the ovaries during a woman's cycle, sperm cannot fertilize it in pregnancy.  Depo-Provera also causes changes in the lining of the uterus that makes it less likely for pregnancy to occur.

Depo-Provera is 99.7% effective, making it one of the most reliable methods of birth control available.

Advantages:
  • Does not contain estrogen, which is a hormone found in most oral contraceptives
  • A long lasting form of contraception that gives contraceptive protection for the next 3 months - there is no daily pill to remember
  • Cannot be expelled from the body, as can sometimes happen with IUD's
  • Offers greater convenience and privacy than barrier methods
  • Is reversible - when wanting to stop using Depo-Provera, simply do not get the next injection. Most women can get pregnant within 12-18 months after the last injection.
  • Can be used by nursing mothers
  • It is private.  With Depo-Provera, there are no packets to keep track of and it cannot be seen or felt, like implants sometimes can
Disadvantages
  • During the first year of use, most women who use Depo-Provera will note changes in their menstrual periods. These changes could include...
    • Irregular or unpredictable bleeding or spotting
    • Increase or decrease in menstrual bleeding
    • No bleeding at all
It is important to note that any unusually heavy or continuous bleeding should be reported to a health care provider.  Lack of menstruation when using Depo-Provera does not mean a woman is pregnant if she has been receiving injections regularly every 3 months.  

Side effects include, most commonly:
  • Irregular Menstrual Bleeding                    
  • Amenorrhea
  • Weight Gain                            
  • Headaches
  • Nervousness                            
  • Stomach Pain or Cramps
  • Dizziness                            
  • Weakness or Fatigue
  • Decreased Sex Drive
  • Many women who experience side effects during the first few months of use report that these decrease over time.
You should not use Depo-Provera if you:
  • Think you might be pregnant
  • Have any undiagnosed vaginal bleeding
  • Have had cancer of the breast or reproductive organs
  • Have had a stroke
  • Have or have had blood clots (phlebitis) in your legs
  • Have had problems with your liver or liver disease
  • Are allergic to Depo-Provera (medroxyprogesterone acetate or any of its other ingredients)

Hudson Health Center
Athens, Ohio 45701
T: (740) 593-1660
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