My research focuses on: 

• Use of a proteomic platform to identify new biomarkers of pre-diabetes, aging, GH doping, and white adipose depot physiology

• Use of a Growth Hormone receptor antagonist to ascertain Growth Hormone's anti-insulin (diabetogenic) action

• Function of the Growth Hormone Receptor in liver, adipose, and muscle tissue as it relates to insulin resistance and aging

• Function of Growth Hormone Binding Protein as it relates to GH's diabetogenic activity.

•  Complete Curriculum Vitae (PDF)

Selected Publications

• List EO, Berryman DE, Funk K, Gosney ES, Jara A, Kelder B, Wang X, Kutz L, Troike K, Lozier N, Mikula V, Lubbers ER, Zhang H, Vesel C, Junnila RK, Frank SJ, Masternak MM, Bartke A, Kopchick JJ.  The Role of GH in Adipose Tissue: Lessons from Adipose-Specific GH Receptor Gene-Disrupted Mice.  Mol Endocrinol. 2013 Jan 24. [Epub ahead of print] PMID:23349524

• Lubbers ER, List EO, Jara A, Sackmann-Sala L, Cordoba-Chacon J, Gahete M, Kineman RD, Boparai R, Bartke A, Kopchick J, Berryman DE.  Adiponectin in mice with altered growth hormone action: links to insulin sensitivity and longevity?  J Endocrinol. 2012 Dec 21. [Epub ahead of print] PMID:23261955

• List EO, Berryman DE, Wright-Piekarski J, Jara A, Funk K, Kopchick JJ.  The effects of weight cycling on lifespan in male C57BL/6J mice.  Int J Obes (Lond). 2012 Dec 11. doi: 10.1038/ijo.2012.203. [Epub ahead of print] PMID: 23229739

• Martos-Moreno GA, Kopchick JJ, Argente J.  Adipokines in healthy and obese children.  An Pediatr(Barc). 2012 Nov 23. doi:pii: S1695-4033(12)00467-5. 10.1016/j.anpedi.2012.10.008. [Epub ahead of print] PMID: 23228441

• Martos-Moreno GA, Sackmann-Sala L, Berryman DE, Blome DW, Argente J, Kopchick JJ.  Anatomical heterogeneity in the proteome of human subcutaneous adipose tissue.  An Pediatr (Barc). 2012 Nov 23. doi:pii: S1695-4033(12)00469-9. 10.1016/j.anpedi.2012.10.010. [Epub ahead of print] PMID: 23228439 

• Ding J, Sackmann-Sala L, Kopchick JJ.  Mouse models of growth hormone action and aging: A proteomic perspective.  Proteomics. 2012 Sep 28. doi: 10.1002/pmic.201200271. [Epub ahead of print] PMID:  23019135

• Burgos-Ramos E, Sackmann-Sala L, Baquedano E, Cruz-Topete D, Barrios V, Argente J, Kopchick JJ.  Central leptin and insulin administration modulates serum cytokine- and lipoprotein-related markers.  Metabolism. 2012 Nov;61(11):1646-57. doi: 10.1016/j.metabol.2012.05.001. Epub 2012 Jun 1. PMID: 22658937

• Ding J, Berryman DE, Jara A, Kopchick JJ.  Age- and sex-associated plasma proteomic changes in growth hormone receptor gene-disrupted mice.  J Gerontol A Biol Sci Med Sci. 2012 Aug;67(8):830-40. doi: 10.1093/gerona/glr212. Epub 2011 Dec 7. PMID: 22156438

• Masternak MM, Bartke A, Wang F, Spong A, Gesing A, Fang Y, Salmon AB, Hughes LF, Liberati T, Boparai R, Kopchick JJ, Westbrook R.  Metabolic effects of intra-abdominal fat in GHRKO mice.  Aging Cell. 2012 Feb;11(1):73-81. doi: 10.1111/j.1474-9726.2011.00763.x. Epub 2011 Nov 28. PMID: 22040032 [PubMed - indexed for MEDLINE]

• Sackmann-Sala L, Berryman DE, Lubbers ER, Vesel CB, Troike KM, List EO, Munn RD, Ikeno Y, Kopchick JJ.  Decreased insulin sensitivity and increased oxidative damage in wasting adipose tissue depots of wild-type mice.  Age (Dordr). 2012 Oct;34(5):1225-37. Epub 2011 Sep 29.  PMID: 21953241

• Ding J, List EO, Bower BD, Kopchick JJ.  Differential effects of growth hormone versus insulin-like growth factor-I on the mouse plasma proteome.  Endocrinology. 2011 Oct;152(10):3791-802. doi: 10.1210/en.2011-1217. Epub 2011 Jul 26. PMID: 21791560

• Sackmann-Sala L, Berryman DE, Munn RD, Lubbers ER, Kopchick JJ.  Heterogeneity among white adipose tissue depots in male C57BL/6J mice.  Obesity (Silver Spring). 2012 Jan;20(1):101-11. doi: 10.1038/oby.2011.235. Epub 2011 Jul 21.  PMID: 21779095

For more publication please link to PubMed.

Awards and Honors

Feb.,  2013       Elected to the National Academy of Inventors Chartered Fellows

Dec.,  2012       Ohio University Distinguished Professorship

Oct.,  2012       Elected President of the Growth Hormone Research Society, Munich,
                          Germany

Apr.,  2012       Ohio Patent Impact Award

Apr.,  2011       British Endocrine Society Transatlantic Medal, Birmingham, England

Aug., 2010       Philips Medal,  Heritage College of Osteopathic Medicine, Ohio University,
                          Athens, Oh.

May,  2008      Commencement Address, Graduation Ceremony, Indiana University of
                          Pennsylvania, Indiana, Pa.

May,  2008       Honorary Doctor of Science Degree, Indiana University of Pennsylvania,
                          Indiana, Pa.

Sep.,  2007       New York College of Osteopathic Medicine's Riland Award.  The Riland
                          Medal is awarded to individuals who have made outstanding contributions
                          to medical science and education, health policy, public policy.

Apr.,  2007       AMVETS Silver Helmet Award.  Highest award given by the AMVETS for
                          service to the USA.

Jan.,  2007       Elected to Growth Hormone Society Research Council

Nov., 2006       Distinguished Alumnus Award, The Graduate School of Biomedical Sciences,
                          University of Texas, Houston, Texas

Dec., 2002        Distinguished Alumnus Award 2002, The University of Texas M.D. Anderson
                          Cancer Center, Houston, Texas

1987-Present    The Milton and Lawrence H. Goll Eminent Scholar Endowed Professorship
                          in Molecular and Cellular Biology, Ohio University, Athens, OH

Related Links

Edison Biotechnology Institute
HCOM Biomedical Sciences
Diabetes Institute Investigator Highlight