My overall research interests are the diabetes prevention and β-cell preservation in type 2 diabetes mellitus (T2DM). One key area is to better understand the phenomena of "metabolic memory" & "legacy effect" of diabetes control observed in clinical trials. The current project is to study the "legacy effect" of glycemic control after short-term insulin therapy in a high-fat diet induced T2DM mouse model.

Selected Publications

• Guo, A.L., Daniels, N.A., Thuma, J., McCall, K., Halko, M, Ycoub,F., Schwartz, F (2013). Diet control is critical for the "legacy" effect of insulin therapy on glycemic control in high fat diet-induced type 2 diabetic mice. Submitted to the 2013 American Diabetes Association (ADA) Annual Meeting.

• Guo, A.L., Daniels, N.A., Kerrigan, K., McCall, K., Thuma, J., Schwartz, F. (2012). Insulin treatment improves β-cell function in high fat diet-induced type 2 diabetic mice. Diabetes (2012; 61: suppl.1, A542, 2132P) .

For more publications please link to PubMed.

Related Links

Heritage College of Osteopathic Medicine