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Bioinformatics Laboratory

Areas of Research. The Bioinformatics Laboratory (BL) invents new computational methods to help answer research questions in domains such as medicine, agriculture, and exercise physiology.  The BL activities involve five faculty from the School of Electrical Engineering and Computer Science, and include research projects in many areas of computational bioscience, including computational regulatory genomics, functional genomics, proteomics, image analysis, data mining, algorithm design and analysis, genetic algorithms and genetic simulators.  

Collaborating Faculty and Institutions. Faculty in other units at Ohio University (such as the Edison Biotechnology Institute, the Genomics Facility, the Department of Environmental and Plant Biology, the Department of Biomedical Sciences, the Biomedical Engineering Program, the Department of Industrial and Systems Engineering, and the Department of Biological Sciences) work with the BL to solve life sciences research problems.  The BL also collaborates with individuals at numerous organizations, including the National Human Genome Research Institute, the Air Force Research Lab, Ohio State University, the Ohio Agricultural Research and Development Center, the Ohio Supercomputer Center, Harvard University, Bowling Green State University, University of Kentucky, and Vanderbilt University

Resources. The BL provides state-of-the-art computational resources, featuring a 5-node cluster computer that has on each node 32GB RAM, 8 cores, 2TB hard disk space (a RAID5 array) and a dual-channel, gigabit ethernet.  Staff support is provided for maintenance and upgrades for the cluster computer.

Journal Club 2011                   Bioinfo Lab Personnel -1- preview

Bioinformatics Colloquium Series

Great Lakes Bioinformatics Conference

WordSeeker: bioinformatics toolkit for regulatory genomics

Careers in Bioinformatics




  • 2011 Russ Prize awarded to Dr. Leroy Hood for his pioneering work on the sequencing of the human genome. Full Article


What is Bioinformatics? What skills are required for this field? What jobs exist in this field and what skills are needed for success in such jobs?

(From Bureau of Labor Statistics) - Conduct research using bioinformatics theory and methods in areas such as pharmaceuticals, medical technology, biotechnology, computational biology, proteomics, computer information science, biology and medical informatics. May design databases and develop algorithms for processing and analyzing genomic information, or other biological information. 

Tasks: (From Bureau of Labor Statistics)

  • Analyze large molecular datasets such as raw microarray data, genomic sequence data, and proteomics data for clinical or basic research purposes.
  • Consult with researchers to analyze problems, recommend technology-based solutions, or determine computational strategies.
  • Manipulate publicly accessible, commercial, or proprietary genomic, proteomic, or post-genomic databases.
  • Communicate research results through conference presentations, scientific publications, or project reports.
  • Compile data for use in activities such as gene expression profiling, genome annotation, and structural bioinformatics.
  • Create novel computational approaches and analytical tools as required by research goals.
  • Create or modify web-based bioinformatics tools.
  • Design and apply bioinformatics algorithms including unsupervised and supervised machine learning, dynamic programming, or graphic algorithms.
  • Develop data models and databases.
  • Develop new software applications or customize existing applications to meet specific scientific project needs.

See http://www.iscb.org/iscb-careers for a listing of career opportunities in bioinformatics. 

Projected growth (2008-2018): Faster than average (14% to 19%) [(From Bureau of Labor Statistics)]

Projected job openings (2008-2018): 16,100 [(From Bureau of Labor Statistics)]



Center for Intelligent, Distributed and Dependable Systems
Russ College of Engineering and Technology
Ohio University
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