Selected Publications and Presentations
Synthesis and structure-activity relationship of
fluoro analogues of 8-{2-[4-(4-methoxyphenyl)piperazin-1yl]ethyl}
-8-azaspiro[4.5]decane-7,9-dione as selective alpha(1d)-adrenergic receptor antagonists. Konkel, M.J.; Wetzel, J.M.; Cahir, M.; Craig, D.A.; Noble, S.A.; Gluchowski, C. (2005) Journal of Medicinal Chemistry 48(8), 3076-3079.
3-Phenyl-2-indolylcarbohydrazide and their azo analogues as potent antagonists for the GalR3 receptor. Topiwala, U.P.; Chen, H.; Jimenez, H.; Reitman, M.; Wetzel, J.M.; Walker, M.; Han, K.; Boyle, N.; Caputo, G.; Muske, G.; Konkel, M.J. (2004) Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, MEDI-030.
Discovery of SNAP 7941 and analogs as high affinity MCH-1 antagonists. Marzabadi, M.R.; DeLeon, J.; Daniewska, I.; Jiang, Y.; Lagu, B.; Li, B.; Wang, Z.; Forray, C.; Borowsky, B.; Ogozalek, K.; Lichtblau, H.; Lim, K.; Tian, D.; Gluchowski, C.; Noble, S.A.; Wetzel, J.M. (2002) Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, MEDI-340.
Identification and characterization of two G protein-coupled receptors for neuropeptide FF. Bonini, J.A.; Jones, K.A.; Adham, N.; Forray, C.; Artymyshyn, R.; Durkin, M.M.; Smith, K.E.; Tamm, J.A.; Boteju, L.W.; Lakhlani, P.P.; Raddatz, R.; Yao, W.-J.; Ogozalek, K.L.; Boyle, N.; Kouranova, E.V.; Quan, Y.; Vaysse, P.J.; Wetzel, J.M.; Branchek, T.A.; Gerald, C.; Borowsky, B. (2000) Journal of Biological Chemistry 275(50), 39324-39331.
Determination of the relative and absolute stereochemistry of a potent and α1A-selective adrenoceptor antagonist. Lagu, B.; Wetzel, J.M.; Forray, C.; Patane, M.A.; Bock, M.G. (2000) Bioorganic & Medicinal Chemistry Letters 10(24), 2705-2707.
De novo design of a novel oxazolidinone analogue as a potent and selective α1A adrenergic receptor antagonist with high oral bioavailability. Lagu,B.; Tian, D.; Jeon, Y.; Li, C.; Wetzel, J.M.; Nagarathnam, D.; Shen, Q.; Forray, C.; Chang, R.S.L.; Broten, T.P.; Ransom, R.W.; Chan, T.-B.; O'Malley, S.S.; Schorn, T.W.; Rodrigues, A.D.; Kassahun, K.; Pettibone, D.J.; Freidinger, R.; Gluchowski, C. (2000) Journal of Medicinal Chemistry 43(15), 2775-2778
